1. - Matthews Lillard,  Scooby-Doo. 2002.  "Confirmed"  as Shaggy  in September 2000. So it goes.

2. - Gael Garcia Bernal, La Science des reves, France,  2005. Rhys was approached to play the part of Stephane Miroux by Michel Grondry, who made Human Nature with him, 2001.  The role went from a Welshman to a Mexican

3. -  Danny Huston, Robin Hood, 2009. As directors changed from Sam Raimi to Bryan Singer to Jon Turtletaub, there was a moment when  the Nottingham reboot had Ifans as the lion-hearted King Richard.  Sir Ridley Scott went with Huston